Clinical Research Program

Endometriosis Study

If you’re interested in participating in a paid clinical research study for patients with endometriosis, fill out the form below.

Paid clinical research study on endometriosis treatment

VPFW is partnering with Clinical Research Partners on a research study to evaluate an oral investigational medication’s ability reduce moderate to severe endometriosis-associated pain.

Purpose of the study

The purpose of this study is to assess the safety and efficacy of different doses of linzagolix alone and in combination with so-called ‘add-back therapy’ compared to placebo (an inactive substance) in women with moderate to severe pain associated with endometriosis.

Description of endometriosis study

Endometriosis is a hormone-dependent condition in which tissue that normally grows inside the uterus grows outside the uterus. It is one of the most common gynecological diseases. The condition is predominantly found in women in their reproductive years and disappears spontaneously after menopause.

Linzagolix is an experimental drug which is not approved by health authorities such as the US Food and Drug Administration (FDA) for the treatment of moderate to severe pain associated with endometriosis. Linzagolix is a new oral drug, a Gonadotropin-Releasing Hormone (GnRH) antagonist. It has been shown to significantly reduce pain associated with endometriosis in women with endometriosis at once daily doses between 50 and 200 mg with a good safety and tolerability profile. Linzagolix reduces the production of sex hormones such as luteinizing hormone and estradiol. The level of hormone reduction is dependent on the dose of linzagolix. About 450 women will take part in this study at a number of different locations in the US and Canada.


You may qualify to participate in the study if you:

  • Are premenopausal, 18-49 years old
  • Have regular menstrual cycles
  • Have moderate to severe pain due to endometriosis during most recent menses and while off menses
  • Are not pregnant or actively trying to get pregnant
  • Do not have osteoporosis or any bone disease


This study has a commitment duration of up to 21 months with 16 visits.


If you qualify and decide to participate, you may receive up to $2,050.00 if all scheduled visits are completed.


If you have any questions about participating in this research study, call Heather at 804-893-0645.

Interested in participating in a paid endometriosis clinical research trial?

If you’d like to participate in a clinical research trial, please complete the form below and we will reach out as studies become available. Thank you for helping us move science forward.